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Hexetidine (Bactidol®) Gargle

Sore throat is one of the most common complaints brought to the attention of otolaryngologists. It may be symptomatic of a variety of illnesses, which is why the treatment must be matched to the individual.

Gargling is an effective and necessary remedy when you have a sore throat. It helps physically clear the deposits and by-products left by the micro-organisms from the mucous membranes of the throat.

Product Details

Each 100 mL contains Hexetidine 100 mg and alcohol 9%.

PHARMACODYNAMICS

The antibacterial effect of Hexetidine (BACTIDOL®) is linked to the suppression of the oxidative reactions of the metabolism of the bacteria (thiamine antagonist). The product possesses a wide spectrum of antibacterial and anti-fungal effects, particularly in relation to gram-positive bacteria and fungi belonging to the Candida genus, but Hexetidine (BACTIDOL®) can also be effective in treating infections caused by Pseudomonas aeruginosa or Proteus species, for example. The product suppresses most bacterial strains in concentrations of 100 mg/ml. Drug-resistance has not been observed. Hexetidine has a mild anaesthetic effect on the mucous membranes.

PHARMACOKINETICS

Hexetidine adheres to the mucous membranes very effectively and is practically not absorbed by them.

After a single application of the active ingredient, its effects on the gingival mucosa are in evidence within 65 hours. Active concentrations remain in the bacterial plaque for 10-14 hours after use.

Refer to product label for complete details.

For Sore Throat: Soothe and give temporary relief of minor sore throat.

For General Oral Hygiene: Marked beneficial effects on color and tone of mouth tissues and helps maintain healthy gums.

For Tooth Decay: Provides continuing protective action on tooth surfaces and kills bacteria that form decay acids.

For Bad Breath: Reduce bad breath all day and night.

WARNING

If prompt relief is not obtained, or if soreness persists or spreads, discontinue use and consult a physician. Fever, headache, nausea and/or vomiting usually indicate severe infection requiring an advice from a physician.

Use in children: Supervise children ages 6-12 years when using Hexetidine

(BACTIDOL®). Do not administer to children <6 years unless directed by a physician.

DOSAGE AND ADMINISTRATION

For adults and children over 12: Swish and gargle (full strength) half a mouthful (20 mL) for 30 sec twice daily (morning and evening). Liquid should be expelled and not be swallowed.

Supervise children ages 6-12 years when using Hexetidine (BACTIDOL®). Do not administer to children <6 years unless directed by a physician.

A doctor should determine the length of the treatment.

What is Sore Throat?

Sore throat is characterized by a painful, itchy, swollen, or irritated throat. Il's offen caused by a viral infection, and it's usually the first sign of a cold. If not treated properly, it can worsen into a cough or flu.

Reference:

1Wile DB. Hexetidine: A report on its antibacterial and antifungal properties on the oral flora in healthy subjects. Cur. Med. Res. Opin. (1986), p. 12

2Ministry of Health of the Russian Federation Federal State Budget Institution. Study of in vitro antiviral activity of Hexetidine against a number of viruses causing acute respiratory infection. 2014 (Data on File)

3Deryabin PG et. Al. Bulletin of Experimental Biology and Medicine, Vol. 160, No. 3, January 2016 VIROLOGY

4The telegraph. Accessed from http://www.telegraph.co.uk/finance/jobs/8806388/Top-10-causes-of-absenteeism.html . Accessed on 6 May 2016

ASC No. J124P010620B, J139P012320B, J140P012320B, J113P011420B, J114P011420B, J121P011420B, J122P011420B, J123P011420B, J113P012120B, J115P012120B, J117P012120B, J127P012120B, J130P012120B, J132P012120B, J152P012120B, J154P012120B, J157P012120B, J185P012120B, J186P012120B, J188P012120B, J191P012120B, J201P012120B, J203P012120B, J205P012120B, J206P012120B, J207P012120B, J208P012120B, J209P012120B, J210P012120B, J211P012120B, J097P012220B, J118P012220B, J120P012220B, J135P012220B, J137P012220B, J139P012220B, J140P012220B, J141P012220B, J143P012220B, J144P012220B, J145P012220B, J147P012220B, J164P012220B, J165P012220B, J167P012220B, J168P012220B, J169P012220B, J170P012220B, J171P012220B, J172P012220B, J125P012320B, J120P012320B, J136P012420B, J136P012320B, J137P012320B, J109P010620B, J111P010620B, J112P010620B, J113P010620B, J115P010620B

If symptoms persist, consult your doctor.